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Argyrophil cell density in the oxyntic mucosa is higher in female than in male morbidly obese patients BJMBR
Maksud,F.A.N.; Kakehasi,A.M.; Barbosa,A.J.A..
Obesity is a multifactorial disorder often associated with many important diseases such as diabetes, hypertension and other metabolic syndrome conditions. Argyrophil cells represent almost the total population of endocrine cells of the human gastric mucosa and some reports have described changes of specific types of these cells in patients with obesity and metabolic syndrome. The present study was designed to evaluate the global population of argyrophil cells of the gastric mucosa of morbidly obese and dyspeptic non-obese patients. Gastric biopsies of antropyloric and oxyntic mucosa were obtained from 50 morbidly obese patients (BMI >40) and 50 non-obese patients (17 dyspeptic overweight and 33 lean individuals) and processed for histology and Grimelius...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Argyrophil cells; Endocrine cells; Obesity; Gastric mucosa; Metabolic syndrome.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000400339
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Ghrelin plasma levels, gastric ghrelin cell density and bone mineral density in women with rheumatoid arthritis BJMBR
Maksud,F.A.N.; Kakehasi,A.M.; Guimarães,M.F.B.R.; Machado,C.J.; Barbosa,A.J.A..
Generalized bone loss can be considered an extra-articular manifestation of rheumatoid arthritis (RA) that may lead to the occurrence of fractures, resulting in decreased quality of life and increased healthcare costs. The peptide ghrelin has demonstrated to positively affect osteoblasts in vitro and has anti-inflammatory actions, but the studies that correlate ghrelin plasma levels and RA have contradictory results. We aimed to evaluate the correlation between total ghrelin plasma levels, density of ghrelin-immunoreactive cells in the gastric mucosa, and bone mineral density (BMD) in twenty adult women with established RA with 6 months or more of symptoms (mean age of 52.70±11.40 years). Patients with RA presented higher ghrelin-immunoreactive cells...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ghrelin; Gastric mucosa; Bone metabolism; Osteoporosis; Rheumatoid arthritis.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000600704
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